From WisPolitics.com/WisBusiness.com …
— WARF is seeking commercial partners to help develop a new method for tracking living cells, which has applications in developing cell therapies.
UW-Madison researchers created this method, which uses an imaging technique called positron emission tomography or PET to track cells within the body. By chemically modifying structures on the surface of cells through a process called radiolabeling, this approach results in “simpler and more powerful” cell tracking.
An overview from the Wisconsin Alumni Research Foundation notes cell therapy offers a “novel and promising approach” to treating a wide array of diseases, ranging from cancer and diabetes to heart attacks and arthritis. This type of therapy uses genetically engineered white blood cells to fight disease.
Authors note tracking cell dynamics within the body is a “key component” for creating new cell therapies, and the new technique “could significantly enhance the development capabilities for accurate, efficacious and safe” treatments. That includes stem cell-based therapies and others.
Its applications for cell therapy development include selecting patients, predicting responses to treatment, evaluating toxicity and more, WARF says. The technique can also be used in quality control for manufacturing cell therapies.
The approach increases the stability of radiolabeled cells and creates a greater “labeling yield,” making it easier for PET scans to detect smaller numbers of injected cells as they move through the body.
“By facilitating accurate and precise preclinical and clinical studies, this technology may accelerate the translation of cell therapies to humans,” authors wrote.
The technology was created by Reinier Hernandez, an assistant professor of medical physics whose work aims to solve problems across the biomedical research field and create new life-saving products.
Top Stories
– US FDA to shorten review time for drug developers under new voucher program
– Sanders asks Cassidy to launch investigation into RFK Jr.’s purge of vaccine panel
– South Africa Built a Medical Research Powerhouse. Trump Cuts Have Demolished It.
– ‘MAGA’ Backers Like Trump’s ‘Big Beautiful Bill’ — Until They Learn of Health Consequences
– The Price You Pay for an Obamacare Plan Could Surge Next Year
– Oz to pitch GOP senators on need for Medicaid changes
– Mark Cuban’s Cost Plus partners with telehealth firm to offer employers obesity care drugs
Press Releases
