UW Stem Cell & Regenerative Medicine Center, BioPharmaceutical Technology Center Institute: Annual stem cell symposium to focus on reprogramming & controlling stem cell phenotype

CONTACT: Karin Borgh, (608) 277-2508, [email protected]

MADISON – The 6th Annual Wisconsin Stem Cell Symposium, Reprogramming& Controlling Stem Cell Phenotype, will be held on April 27, 2011 in Madison, WI. Talks provided by world leaders in the area of cellular reprogramming will focus on using intracellular or extracellular cues to manipulate gene regulation and control stem cell pluripotency and lineage-specific differentiation.

This public symposium is co-coordinated by the University of Wisconsin Stem Cell & Regenerative Medicine Center, and the BioPharmaceutical Technology Center Institute. These organizations, along with Michael Best & Friedrich LLP, EMD Millipore Corporation, Promega Corporation and WiCell Research Institute, are serving as Platinum Sponsors.

Featured presenters include: Kristi S. Anseth, of the University of Colorado-Boulder; Helen M. Blau of Stanford University; Sheng Ding of The Scripps Research Institute, La Jolla, CA; John Gurdon of the University of Cambridge, UK; Juan Carlos Izpisúa Belmonte of the Salk Institute for Biological Studies, La Jolla, CA; Stuart H. Orkin of Harvard University; Laura Kiessling and James A. Thomson of the University of Wisconsin-Madison.

Questions to be addressed include:

*How can we understand and manipulate gene regulation to control stem cell self-renewal and lineage-specific differentiation?

*What are the signaling mechanisms that are shared among multiple stem cell types?

*What are the key mechanisms by which natural stem cell niches influence phenotype?

*Can components of natural stem cell niches be effectively mimicked to control stem cell phenotype?

*How can somatic cells be reprogrammed to pluripotent phenotype using intracellular or extracellular cues?

The daylong symposium, which is open to the public with a registration fee of $90, will be held at Promega Corporation’s BioPharmaceutical Technology Center, 5445 E. Cheryl Parkway, Fitchburg, WI. For more information, please visit http://www.btci.org